Basic information  Ambroxol hydrochloride is a small molecule expectorant and mucolytic agent with antioxidant and antiinflammatory effects. Ambroxol stimulates the secretion of surfactant which decreases mucus adhesion to the bronchial lining and produces expectorant effects. The antioxidant effects of Ambroxol are well demonstrated, where lipid peroxidation initiated by t-butyl hydroperoxide or doxorubicin is suppressed in the presence Ambroxol, and scavenging of hydroxyl radicals and cellular superoxide radical anions is also observed. Ambroxol produces antiinflammatory effects by blocking the expression of proinflammatory messengers, inhibiting the release of histamine from mast cells and the generation of cytokines and interleukins. Ambroxol hydrochloride is an inhibitor of Sodium Channel Protein.  Test items Standard Imported Drug Registration Standard Characters White  powder. White to pale yellowish white powder. Heavy metals Not more than 10ppm Not more than 10ppm Related substances Individual impurity <0.1% Total impurities < 1.0% Total impurities < 1.5%  Loss on drying Not more than 1.0% Not more than 1.0% Assay 98.0%-100.0% Not less than 99.0%  Basic information  Ambroxol hydrochloride is a small molecule expectorant and mucolytic agent with antioxidant and antiinflammatory effects. Ambroxol stimulates the secretion of surfactant which decreases mucus adhesion to the bronchial lining and produces expectorant effects. The antioxidant effects of Ambroxol are well demonstrated, where lipid peroxidation initiated by t-butyl hydroperoxide or doxorubicin is suppressed in the presence Ambroxol, and scavenging of hydroxyl radicals and cellular superoxide radical anions is also observed. Ambroxol produces antiinflammatory effects by blocking the expression of proinflammatory messengers, inhibiting the release of histamine from mast cells and the generation of cytokines and interleukins. Ambroxol hydrochloride is an inhibitor of Sodium Channel Protein.  Test items Standard Imported Drug Registration Standard Characters White  powder. White to pale yellowish white powder. Heavy metals Not more than 10ppm Not more than 10ppm Related substances Individual impurity <0.1% Total impurities < 1.0% Total impurities < 1.5%  Loss on drying Not more than 1.0% Not more than 1.0% Assay 98.0%-100.0% Not less than 99.0% Â
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CAS No:23828-92-4 Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Einecs No.: N/A
Character:White  powder                                MF: C14H21Br2ClN2
MW:414.56376 Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Purity:99%
Quality Guarantee Period:Two Years Min                  Grade Standard:enterprise standard
Sample:10-20g Free Sample                              Brand Name:Wongpharm
Ambroxol hcl CAS 23828-92-4
Molecular formula:23828-92-4 Â
Molecular weight:Â 414.56376 Â Â Â Â
Character:White  powder    Â
Main use:
Expectorant has good mucolysis effect and lubricating respiratory tract effect. It can promote the secretion of pulmonary surfactant, respiratory fluid secretion and cilia movement, etc. It is used in the treatment of acute and chronic respiratory diseases, abnormal bronchial secretion and so on.
Pharmacological toxicology:
This product has the characteristics of mucus exclusion, promotion and dissolution of secretions. It can promote the removal of viscous secretions from the respiratory tract and reduce the retention of mucus, thus significantly promoting the discharge of phlegm and improving the respiratory status. The secretion of mucus returns to normal. Coughing and sputum volume are usually significantly reduced, and the surfactant on the mucous membrane of the respiratory tract thus performs its normal protective function.
Pharmacokinetics:
The half-life was 7-12 hours, no accumulation was found, and 90% of the liver metabolites were cleared by the kidney.
Indication:
For acute, chronic respiratory diseases with abnormal sputum secretion and poor sputum function, such as acute exacerbation of chronic bronchitis, asthmatic bronchitis, and expectorant treatment of bronchial asthma;
Quality standard:Â enterprise standard
Content: ≥ 98.0%
Package:25kg/drum
specification
CAS No:23828-92-4 Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Einecs No.: N/A
Character:White  powder                                MF: C14H21Br2ClN2
MW:414.56376 Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Purity:99%
Quality Guarantee Period:Two Years Min                  Grade Standard:enterprise standard
Sample:10-20g Free Sample                              Brand Name:Wongpharm
Ambroxol hcl CAS 23828-92-4
Molecular formula:23828-92-4 Â
Molecular weight:Â 414.56376 Â Â Â Â
Character:White  powder    Â
Main use:
Expectorant has good mucolysis effect and lubricating respiratory tract effect. It can promote the secretion of pulmonary surfactant, respiratory fluid secretion and cilia movement, etc. It is used in the treatment of acute and chronic respiratory diseases, abnormal bronchial secretion and so on.
Pharmacological toxicology:
This product has the characteristics of mucus exclusion, promotion and dissolution of secretions. It can promote the removal of viscous secretions from the respiratory tract and reduce the retention of mucus, thus significantly promoting the discharge of phlegm and improving the respiratory status. The secretion of mucus returns to normal. Coughing and sputum volume are usually significantly reduced, and the surfactant on the mucous membrane of the respiratory tract thus performs its normal protective function.
Pharmacokinetics:
The half-life was 7-12 hours, no accumulation was found, and 90% of the liver metabolites were cleared by the kidney.
Indication:
For acute, chronic respiratory diseases with abnormal sputum secretion and poor sputum function, such as acute exacerbation of chronic bronchitis, asthmatic bronchitis, and expectorant treatment of bronchial asthma;
Quality standard:Â enterprise standard
Content: ≥ 98.0%
Package:25kg/drum
specification
Expectorants Powder Ambroxol Hydrochloride CAS 23828-92-4
Model NO.: 99%
Einecs No.: N/a
Character: White Powder.
Mf: C13h19br2cln2o
MW: 414.56376
Purity: 99%
Quality Guarantee Period: Two Years Min
Grade Standard: Enterprise Standard
Sample: 10-20g Free Sample
Brand Name: Wongpharm
Trademark: wongpharm
Transport Package: 25kg/Drum
Specification: 99%
Origin: China (Mainlan)
Model NO.: 99%
Einecs No.: N/a
Character: White Powder.
Mf: C13h19br2cln2o
MW: 414.56376
Purity: 99%
Quality Guarantee Period: Two Years Min
Grade Standard: Enterprise Standard
Sample: 10-20g Free Sample
Brand Name: Wongpharm
Trademark: wongpharm
Transport Package: 25kg/Drum
Specification: 99%
Origin: China (Mainlan)